The Ministry of Health, citing the PRCS, announced that the hospital no longer was operational after running out of fuel and sustaining damage in the direct targeting on November 5, 2023.

The Gaza Media Office reported that the Haifa Charity Hospital was out of service.

The hospital stated that there were no medicines for cancer patients, that more than 2,200 requests for transfers abroad had been submitted, and the hospital administration re-launched an appeal to facilitate travel for the treatment of more than 2,600 cases in need of immediate treatment.

The Ministry of Health announced the death of four cancer patients as a result of the hospital being out of service due to targeting and running out of fuel.

Occupation forces bombed the vicinity of Al-Karama Specialized Hospital, rendering the hospital out of service as buildings adjacent to the hospital fell on it.

As the hospital entered its seventh day of Israeli siege and fifth day without communications, the PRCS announced that the hospital was completely out of service due to lack of available fuel and power outages. Staff continued to provide the best service they could to the injured as the hospital lacked power, food, medical equipment, food, and water. Staff were forced to use traditional medical methods due to the lack of supplies. Displaced people were forced to evacuate to the south on a specific route drawn by the Israeli military.

Occupation forces bombed the hospital.

On November 11,2024,occupation forces tightened the siege of the hospital by advancing towards the hospital's entrance, intensify the airstrikes around the hospital and PRCS headquarters, and fired live ammunition at the intensive care unit and displaced people sheltering in the hospital, causing several injuries. Occupation forces also opened fire at the clinics and at everyone moving outside of the hospital, killing a displaced person.